Detalhe da pesquisa
1.
Vertebrate-class-specific binding modes of the alphavirus receptor MXRA8.
Cell
; 186(22): 4818-4833.e25, 2023 10 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-37804831
2.
Structure-function correlates of fibrinogen binding by Acinetobacter adhesins critical in catheter-associated urinary tract infections.
Proc Natl Acad Sci U S A
; 120(4): e2212694120, 2023 01 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-36652481
3.
Apolipoprotein E4 has extensive conformational heterogeneity in lipid-free and lipid-bound forms.
Proc Natl Acad Sci U S A
; 120(7): e2215371120, 2023 02 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-36749730
4.
SARS-CoV-2 Nsp16 activation mechanism and a cryptic pocket with pan-coronavirus antiviral potential.
Biophys J
; 120(14): 2880-2889, 2021 07 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-33794150
5.
Cooperative Changes in Solvent Exposure Identify Cryptic Pockets, Switches, and Allosteric Coupling.
Biophys J
; 116(5): 818-830, 2019 03 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-30744991
6.
Solid-state NMR evidence for ß-hairpin structure within MAX8 designer peptide nanofibers.
Biophys J
; 105(1): 222-30, 2013 Jul 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-23823242
7.
A cryptic pocket in Ebola VP35 allosterically controls RNA binding.
Nat Commun
; 13(1): 2269, 2022 04 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-35477718
8.
Deep learning the structural determinants of protein biochemical properties by comparing structural ensembles with DiffNets.
Nat Commun
; 12(1): 3023, 2021 05 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-34021153
9.
Naturally Occurring Genetic Variants in the Oxytocin Receptor Alter Receptor Signaling Profiles.
ACS Pharmacol Transl Sci
; 4(5): 1543-1555, 2021 Oct 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-34661073
10.
The SARS-CoV-2 nucleocapsid protein is dynamic, disordered, and phase separates with RNA.
Nat Commun
; 12(1): 1936, 2021 03 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-33782395
11.
SARS-CoV-2 simulations go exascale to predict dramatic spike opening and cryptic pockets across the proteome.
Nat Chem
; 13(7): 651-659, 2021 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-34031561
12.
Computing and optimizing over all fixed-points of discrete systems on large networks.
J R Soc Interface
; 17(170): 20200126, 2020 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-32900299
13.
Conformational distributions of isolated myosin motor domains encode their mechanochemical properties.
Elife
; 92020 05 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-32479265
14.
SARS-CoV-2 Nsp16 activation mechanism and a cryptic pocket with pan-coronavirus antiviral potential.
bioRxiv
; 2020 Dec 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-33330873
15.
Spatial and temporal alterations in protein structure by EGF regulate cryptic cysteine oxidation.
Sci Signal
; 13(615)2020 01 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-31964804
16.
The Cap-Snatching SFTSV Endonuclease Domain Is an Antiviral Target.
Cell Rep
; 30(1): 153-163.e5, 2020 01 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-31914382
17.
The SARS-CoV-2 nucleocapsid protein is dynamic, disordered, and phase separates with RNA.
bioRxiv
; 2020 Dec 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-32587966
18.
SARS-CoV-2 Simulations Go Exascale to Capture Spike Opening and Reveal Cryptic Pockets Across the Proteome.
bioRxiv
; 2020 Oct 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-32637963
19.
Choice of Adaptive Sampling Strategy Impacts State Discovery, Transition Probabilities, and the Apparent Mechanism of Conformational Changes.
J Chem Theory Comput
; 14(11): 5459-5475, 2018 Nov 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-30240203
20.
Designing small molecules to target cryptic pockets yields both positive and negative allosteric modulators.
PLoS One
; 12(6): e0178678, 2017.
Artigo
em Inglês
| MEDLINE | ID: mdl-28570708